Cleveland was founded in the late 1700's near the mouth of the Cuyahoga River. In the 1800's, with the addition of several canals and effective railroad lines, Cleveland quickly became an important manufacturing center.
Cleveland was conveniently connected with the Atlantic Ocean by way of the Erie Canal, and the Gulf of Mexico by way of the Mississippi River.
Railroads of Indiana added many miles of track during the 1850's. So many immigrated to Indiana in that decade, that it became the nation's fourth largest state by 1860, according to population.
During the American Civil War many new branches of Michigan's railroad system were added to transport the state's many manufactures.
This detailed map focusing on Indiana, Michigan and Ohio was published in 1859 by George Woolworth Colton. It displays cities, towns, counties and waterways. The railroad network is clearly labeled including mileage between stations.